09/09/2021
Benzalkoniumchloride, also known as alkyldimethylbenzylammonium chloride and by the trade name Zephiran, is an organic salt used in cleaning agents, classified as a quaternary ammonium cationic detergent and it is the most commonly used antimicrobial preservative. It can be used as an antiseptic and preservative in personal care, healthcare, household, pharmaceutical, and industrial products.
Benzalkonium chlorides (BACs) are chemicals with widespread applications due to their broad-spectrum antimicrobial properties against bacteria, fungi, and viruses.
BACs were reported for the first time in 1935 by Gerhard Domagk,
gaining the market as zephiran chlorides, and were marketed as promising and superior disinfectant and antiseptics. In 1947, the first product containing BACs was registered with the Environmental Protection Agency (EPA) in the United States. Since then, they have been used in a wide variety of products, both prescription and over the counter. Applications range from domestic to agricultural, industrial, and clinical. Domestic applications include fabric softeners, personal hygiene and cosmetic products, such as shampoos, conditioners, and body lotions, as well as ophthalmic solutions and medications that use the nasal route of delivery
